Order NO. D291479
兔抗STAT3单克隆抗体
| 英文名 | Anti-STAT3 rabbit monoclonal antibody | ||
| 别名 | signal transducer and activator of transcription 3; APRF; HIES; ADMIO; ADMIO1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | STAT3 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291479-0050 | 50 ul | 预计5日内发货 |
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| D291479-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020] |
| Applications: | WB, IHC, IF |
| Name of antibody: | STAT3 |
| Immunogen: | Synthetic peptide of human STAT3 |
| Full name: | signal transducer and activator of transcription 3 |
| Synonyms: | APRF; HIES; ADMIO; ADMIO1 |
| SwissProt: | P40763 |
| IHC positive control: | rat brain |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 88 kDa |
| WB Positive control: | A431, Human liver, Mouse heart, Rat brain lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | Hela cells treated with IFN-alpha |
| IF Recommended dilution: | 50-200 |
相关文档
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Sample Application
