Order NO. D291484
兔抗STIM1单克隆抗体
| 英文名 | Anti-STIM1 rabbit monoclonal antibody | ||
| 别名 | stromal interaction molecule 1; GOK; TAM; TAM1; IMD10; STRMK; D11S4896E | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | STIM1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291484-0050 | 50 ul | 预计5日内发货 |
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| D291484-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] |
| Applications: | WB |
| Name of antibody: | STIM1 |
| Immunogen: | Synthetic peptide of human STIM1 |
| Full name: | stromal interaction molecule 1 |
| Synonyms: | GOK; TAM; TAM1; IMD10; STRMK; D11S4896E |
| SwissProt: | Q13586 |
| WB Predicted band size: | 77 kDa |
| WB Positive control: | MCF-7, C6, 3T3, Hela lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
