Order NO. D291623
兔抗UHRF1单克隆抗体
| 英文名 | Anti-UHRF1 rabbit monoclonal antibody | ||
| 别名 | ubiquitin like with PHD and ring finger domains 1; Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | UHRF1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291623-0050 | 50 ul | 预计5日内发货 |
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| D291623-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014] |
| Applications: | WB |
| Name of antibody: | UHRF1 |
| Immunogen: | Fusion protein of human UHRF1 |
| Full name: | ubiquitin like with PHD and ring finger domains 1 |
| Synonyms: | Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95 |
| SwissProt: | Q96T88 |
| WB Predicted band size: | 90 kDa |
| WB Positive control: | K562, Hela lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
