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Order NO. D291679
兔抗ZAP70单克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291679-0050 | 50 ul | 预计5日内发货 |
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| D291679-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Applications: | WB |
| Name of antibody: | ZAP70 |
| Immunogen: | Synthetic peptide of human ZAP70 |
| Full name: | zeta chain of T cell receptor associated protein kinase 70 |
| Synonyms: | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
| SwissProt: | P43403 |
| WB Predicted band size: | 70 kDa |
| WB Positive control: | Jurkat lysate |
| WB Recommended dilution: | 500-2000 |
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