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Order NO. D291696
兔抗Casp4单克隆抗体
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291696-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 | |
D291696-0100 | 100 ul | 预计5日内发货 | 待询价 | 待询价 |
属性
Background: | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015] |
Applications: | WB |
Name of antibody: | Casp4 |
Immunogen: | Fusion protein of mouse Casp4 |
Full name: | caspase 4, apoptosis-related cysteine peptidase |
Synonyms: | Caspl; ich-3; CASP-4; Casp11; CASP-11 |
SwissProt: | P70343 |
WB Predicted band size: | 43 kDa |
WB Positive control: | Rat brain, C6, 3T3 lysates |
WB Recommended dilution: | 500-2000 |
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