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Order NO. D291696
兔抗Casp4单克隆抗体
英文名 Anti-Casp4 rabbit monoclonal antibody
别名 caspase 4, apoptosis-related cysteine peptidase; Caspl; ich-3; CASP-4; Casp11; CASP-11
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 Casp4    
编 号 规格 库存 目录价(¥) 您的价格(¥) 数 量
D291696-0050 50 ul 预计5日内发货 待询价 待询价
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D291696-0100 100 ul 预计5日内发货 待询价 待询价
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属性

Background: This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]
Applications: WB
Name of antibody: Casp4
Immunogen: Fusion protein of mouse Casp4
Full name: caspase 4, apoptosis-related cysteine peptidase
Synonyms: Caspl; ich-3; CASP-4; Casp11; CASP-11
SwissProt: P70343
WB Predicted band size: 43 kDa
WB Positive control: Rat brain, C6, 3T3 lysates
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane 1-3: Rat brain, C6, 3T3 lysates, Primary antibody: D291696(Casp4 Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes