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Order NO. D291743
兔抗Tgfb1单克隆抗体
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英文名 | Anti-Tgfb1 rabbit monoclonal antibody | ||
别名 | transforming growth factor, beta 1; Tgfb; Tgfb-1; TGFbeta1; TGF-beta1 | ||
相关类别 | 一抗 | 储存 | 冷冻(-20℃) |
宿主 | Rabbit | 反应种属 | Human, Mouse, Rat |
标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
抗原 | Tgfb1 | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D291743-0050 | 50 ul | 预计5日内发货 |
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D291743-0100 | 100 ul | 预计5日内发货 |
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属性
Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016] |
Applications: | WB |
Name of antibody: | Tgfb1 |
Immunogen: | Fusion protein of mouse Tgfb1 |
Full name: | transforming growth factor, beta 1 |
Synonyms: | Tgfb; Tgfb-1; TGFbeta1; TGF-beta1 |
SwissProt: | P04202 |
WB Predicted band size: | 44 kDa |
WB Positive control: | Jurkat, C6, RAW264.7 lysates |
WB Recommended dilution: | 500-2000 |