Order NO. D620082
人TP53抗原（重组蛋白）
| 英文名 | Human TP53 Antigen (Recombinant Protein) | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D620082-0001 | 1 MG | 预计7日内发货 |
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| D620082-0050 | 50 UG | 预计7日内发货 |
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| D620082-0100 | 100 UG | 预计7日内发货 |
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产品描述
概述
Recombinant protein corresponding to a region derived from 1-236 amino acids of human TP53
属性
| Full name: | tumor protein p53 |
| Synonyms: | P53; BCC7; LFS1; BMFS5; TRP53 |
| Swissprot: | P04637 |
| Gene Accession: | BC003596 |
| Gene ID: | 7157 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Epigenetics and Nuclear Signaling, Cancer |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] (The background information is obtained from official databases and does not represent the product information.) |
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Sample Application
