Order NO. D620393
人CDC27抗原（重组蛋白）
| 英文名 | Human CDC27 Antigen (Recombinant Protein) | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D620393-0001 | 1 MG | 预计30日内发货 |
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| D620393-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 525-824 amino acids of human CDC27
属性
| Full name: | cell division cycle 27 |
| Synonyms: | APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E |
| Swissprot: | P30260 |
| Gene Accession: | BC011656 |
| Gene ID: | 996 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cancer, Cell Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y. [provided by RefSeq, May 2014] (The background information is obtained from official databases and does not represent the product information.) |
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