Order NO. D620482
人CRP抗原(重组蛋白)
英文名 | Human CRP Antigen (Recombinant Protein) | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D620482-0001 | 1 MG | 预计30日内发货 |
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D620482-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 2-91 amino acids of human CRP
属性
Full name: | C-reactive protein |
Synonyms: | PTX1 |
Swissprot: | P02741-2 |
Gene Accession: | BC020766 |
Gene ID: | 1401 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Epigenetics and Nuclear Signaling, Metabolism, Cardiovascular, Immunology |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020] (The background information is obtained from official databases and does not represent the product information.) |