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Order NO. D620676
人CXCL11抗原(重组蛋白)
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D620676-0001 | 1 MG | 预计30日内发货 |
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D620676-0050 | 50 UG | 预计30日内发货 |
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D620676-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-94 amino acids of human CXCL11
属性
Full name: | C-X-C motif chemokine ligand 11 |
Synonyms: | IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B |
Swissprot: | O14625 |
Gene Accession: | BC005292 |
Gene ID: | 6373 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Immunology, Neuroscience |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] (The background information is obtained from official databases and does not represent the product information.) |