Order NO. D620686
GDF15抗原(重组蛋白)
英文名 | GDF15 Antigen (Recombinant Protein) | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D620686-0001 | 1 MG | 预计30日内发货 |
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D620686-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 195-308 amino acids of human GDF15
属性
Full name: | growth differentiation factor 15 |
Synonyms: | PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15 |
Swissprot: | Q99988 |
Gene Accession: | BC000529 |
Gene ID: | 9518 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Signal Transduction, Cancer, Cardiovascular |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016] (The background information is obtained from official databases and does not represent the product information.) |