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Order NO. D620830
人IL15抗原（重组蛋白）
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D620830-0001 | 1 MG | 预计30日内发货 |
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| D620830-0050 | 50 UG | 预计30日内发货 |
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| D620830-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-162 amino acids of human IL15
属性
| Full name: | interleukin 15 |
| Synonyms: | IL-15 |
| Swissprot: | P40933 |
| Gene Accession: | BC018149 |
| Gene ID: | 3600 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus and N-Terminus |
| Research areas: | Cancer, Metabolism, Immunology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011] (The background information is obtained from official databases and does not represent the product information.) |
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