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Order NO. D620831
人IL18抗原(重组蛋白)
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D620831-0001 | 1 MG | 预计7日内发货 |
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D620831-0050 | 50 UG | 预计7日内发货 |
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D620831-0100 | 100 UG | 预计7日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-193 amino acids of human IL18
属性
Full name: | interleukin 18 |
Synonyms: | IGIF; IL-18; IL-1g; IL1F4 |
Swissprot: | Q14116 |
Gene Accession: | BC007007 |
Gene ID: | 3606 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Cardiovascular, Cancer, Immunology |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] (The background information is obtained from official databases and does not represent the product information.) |