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Order NO. D620990
人MMP14抗原(重组蛋白)
英文名 Human MMP14 Antigen (Recombinant Protein)
别名 MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D620990-0001 1 MG 预计30日内发货
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D620990-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 312-541 amino acids of human MMP14

属性

Full name: matrix metallopeptidase 14
Synonyms: MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
Swissprot: P50281
Gene Accession: BC064803
Gene ID: 4323
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Signal Transduction, Cardiovascular, Cancer, Metabolism, Cell Biology
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
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Sample Application

  • Purified Human MMP14 Recombinant Protein (Catalog number: D620990) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.
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