人MPZ抗原（重组蛋白）,Human MPZ Antigen (Recombinant Protein) 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

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Order NO. D621010

人MPZ抗原（重组蛋白）

英文名	Human MPZ Antigen (Recombinant Protein)
别名	P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB
相关类别	抗原	储存	冷冻（-20℃）
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D621010-0001	1 MG	预计30日内发货	待询价	待询价
D621010-0050	50 UG	预计30日内发货	待询价	待询价
D621010-0100	100 UG	预计30日内发货	待询价	待询价

产品描述

概述

Fusion protein corresponding to a region derived from 1-248 amino acids of human MPZ

属性

Full name:	myelin protein zero
Synonyms:	P0; CHM; DSS; MPP; CHN2; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB
Swissprot:	P25189
Gene Accession:	BC006491
Gene ID:	4359
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Research areas:	Neuroscience
Reconstitution:	Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background:	This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015] (The background information is obtained from official databases and does not represent the product information.)

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