在线客服
网站反馈
网站指南
我的会员中心
中文
我的草稿
我的购物车
Order NO. D621256
人SPAG8抗原（重组蛋白）
英文名 Human SPAG8 Antigen (Recombinant Protein)
别名 SMP1, BS-84, HSD-1, SPAG3, hSMP-1
相关类别 抗原 储存 冷冻（-20℃）
编 号 包装 库存 目录价（￥） 您的价格（￥） 数 量
D621256-0001 1 MG 预计30日内发货
加入购物车
D621256-0050 50 UG 预计30日内发货
加入购物车
D621256-0100 100 UG 预计30日内发货
加入购物车
产品描述

概述

Fusion protein corresponding to a region derived from 205-426 amino acids of human SPAG8

属性

Full name: sperm associated antigen 8
Synonyms: SMP1; BS-84; CT142; HSD-1; SPAG3; CILD28; hSMP-1
Swissprot: Q99932
Gene Accession: BC019247
Gene ID: 26206
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Cancer, Stem Cells
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq, Jul 2012] (The background information is obtained from official databases and does not represent the product information.)
相关文档