Order NO. D621387
人TSG101抗原（重组蛋白）
| 英文名 | Human TSG101 Antigen (Recombinant Protein) | ||
| 别名 | TSG10; VPS23 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D621387-0001 | 1 MG | 预计30日内发货 |
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| D621387-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 2-145 amino acids of human TSG101
属性
| Full name: | tumor susceptibility 101 |
| Synonyms: | TSG10; VPS23 |
| Swissprot: | Q99816 |
| Gene Accession: | BC002487 |
| Gene ID: | 7251 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Epigenetics and Nuclear Signaling, Cancer |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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