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Order NO. D621501
人ADAM15抗原（重组蛋白）
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D621501-0001 | 1 MG | 预计30日内发货 |
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| D621501-0050 | 50 UG | 预计30日内发货 |
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| D621501-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 213-414 amino acids of human ADAM15
属性
| Full name: | ADAM metallopeptidase domain 15 |
| Synonyms: | MDC15 |
| Swissprot: | Q13444 |
| Gene Accession: | BC014566 |
| Gene ID: | 8751 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Signal Transduction, Cell Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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