Order NO. D621827
人PIM1抗原（重组蛋白）
| 英文名 | Human PIM1 Antigen (Recombinant Protein) | ||
| 别名 | PIM | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D621827-0001 | 1 MG | 预计30日内发货 |
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| D621827-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 86-313 amino acids of human PIM1
属性
| Background: | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011] (The background information is obtained from official databases and does not represent the product information.) |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Research areas: | Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Stem Cells |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Expression system: | Escherichia coli |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Gene ID: | 5292 |
| Gene Accession: | BC020224 |
| Swissprot: | P11309 |
| Synonyms: | PIM |
| Full name: | Pim-1 proto-oncogene, serine/threonine kinase |
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