Order NO. D621891
人PGK1抗原（重组蛋白）
| 英文名 | Human PGK1 Antigen (Recombinant Protein) | ||
| 别名 | PGKA; MIG10 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D621891-0001 | 1 MG | 预计30日内发货 |
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| D621891-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 168-417 amino acids of human PGK1
属性
| Full name: | phosphoglycerate kinase 1 |
| Synonyms: | PGKA; MIG10; HEL-S-68p |
| Swissprot: | P00558 |
| Gene Accession: | BC113568 |
| Gene ID: | 5230 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Metabolism, Cancer, Cardiovascular |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014] (The background information is obtained from official databases and does not represent the product information.) |
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