Order NO. D622077
CD46抗原（重组蛋白）
| 英文名 | CD46 Antigen (Recombinant Protein) | ||
| 别名 | MCP; TLX; AHUS2; MIC10; TRA2.10 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D622077-0001 | 1 MG | 预计30日内发货 |
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| D622077-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 35-285 amino acids of human CD46
属性
| Full name: | CD46 molecule |
| Synonyms: | MCP; TLX; AHUS2; MIC10; TRA2.10 |
| Swissprot: | P15529-11 |
| Gene Accession: | BC030594 |
| Gene ID: | 4179 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Immunology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] (The background information is obtained from official databases and does not represent the product information.) |
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