Order NO. D622184
CYP17A1抗原(重组蛋白)
英文名 | CYP17A1 Antigen (Recombinant Protein) | ||
别名 | CPT7; CYP17; S17AH; P450C17 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D622184-0001 | 1 MG | 预计30日内发货 |
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D622184-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 259-508 amino acids of human CYP17A1
属性
Full name: | cytochrome P450 family 17 subfamily A member 1 |
Synonyms: | CPT7; CYP17; S17AH; P450C17 |
Swissprot: | P05093 |
Gene Accession: | BC063388 |
Gene ID: | 1586 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Metabolism, Signal Transduction, Cancer, Cardiovascular |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |