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Order NO. D622184
CYP17A1抗原(重组蛋白)
英文名 CYP17A1 Antigen (Recombinant Protein)
别名 CPT7; CYP17; S17AH; P450C17
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D622184-0001 1 MG 预计30日内发货
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D622184-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 259-508 amino acids of human CYP17A1

属性

Full name: cytochrome P450 family 17 subfamily A member 1
Synonyms: CPT7; CYP17; S17AH; P450C17
Swissprot: P05093
Gene Accession: BC063388
Gene ID: 1586
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Metabolism, Signal Transduction, Cancer, Cardiovascular
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
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