
Order NO. D622365
人CEP43抗原(重组蛋白)
英文名 | Human CEP43 Antigen (Recombinant Protein) | ||
别名 | FOP | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D622365-0001 | 1 MG | 预计30日内发货 |
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D622365-0050 | 50 UG | 预计30日内发货 |
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D622365-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-249 amino acids of human CEP43
属性
Full name: | centrosomal protein 43 |
Synonyms: | FOP; FGFR1OP |
Swissprot: | O95684-2 |
Gene Accession: | BC011902 |
Gene ID: | 11116 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Cell Biology |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] (The background information is obtained from official databases and does not represent the product information.) |