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Order NO. D622365
人CEP43抗原(重组蛋白)
英文名 Human CEP43 Antigen (Recombinant Protein)
别名 FOP
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D622365-0001 1 MG 预计30日内发货
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D622365-0050 50 UG 预计30日内发货
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D622365-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 1-249 amino acids of human CEP43

属性

Full name: centrosomal protein 43
Synonyms: FOP; FGFR1OP
Swissprot: O95684-2
Gene Accession: BC011902
Gene ID: 11116
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Cell Biology
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] (The background information is obtained from official databases and does not represent the product information.)
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