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Order NO. D622520
人HYAL2抗原(重组蛋白)
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D622520-0001 | 1 MG | 预计30日内发货 | 待询价 | 待询价 |
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D622520-0050 | 50 UG | 预计30日内发货 | 待询价 | 待询价 |
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D622520-0100 | 100 UG | 预计30日内发货 | 待询价 | 待询价 |
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产品描述
概述
Fusion protein corresponding to a region derived from 21-300 amino acids of human HYAL2
属性
Full name: | hyaluronidase 2 |
Synonyms: | LUCA2 |
Swissprot: | Q12891 |
Gene Accession: | BC000692 |
Gene ID: | 8692 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Signal Transduction |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010] (The background information is obtained from official databases and does not represent the product information.) |
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