Order NO. D622946
PTPN22抗原(重组蛋白)
英文名 | PTPN22 Antigen (Recombinant Protein) | ||
别名 | LYP; PEP; LYP1; LYP2; PTPN8 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D622946-0001 | 1 MG | 预计30日内发货 |
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D622946-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-179 amino acids of human PTPN22
属性
Full name: | protein tyrosine phosphatase non-receptor type 22 |
Synonyms: | LYP; PEP; LYP1; LYP2; PTPN8; PTPN22.5; PTPN22.6 |
Swissprot: | Q9Y2R2-5 |
Gene Accession: | BC017785 |
Gene ID: | 26191 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Signal Transduction |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009] (The background information is obtained from official databases and does not represent the product information.) |