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Order NO. D622946
PTPN22抗原(重组蛋白)
英文名 PTPN22 Antigen (Recombinant Protein)
别名 LYP; PEP; LYP1; LYP2; PTPN8
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D622946-0001 1 MG 预计30日内发货
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D622946-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 1-179 amino acids of human PTPN22

属性

Full name: protein tyrosine phosphatase non-receptor type 22
Synonyms: LYP; PEP; LYP1; LYP2; PTPN8; PTPN22.5; PTPN22.6
Swissprot: Q9Y2R2-5
Gene Accession: BC017785
Gene ID: 26191
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Signal Transduction
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009] (The background information is obtained from official databases and does not represent the product information.)
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