Order NO. D623112
DHCR24抗原（重组蛋白）
| 英文名 | DHCR24 Antigen (Recombinant Protein) | ||
| 别名 | DCE; SELADIN1; Nbla03646; seladin-1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D623112-0001 | 1 MG | 预计30日内发货 |
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| D623112-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 300-516 amino acids of human DHCR24
属性
| Full name: | 24-dehydrocholesterol reductase |
| Synonyms: | DCE; SELADIN1; Nbla03646; seladin-1 |
| Swissprot: | Q15392 |
| Gene Accession: | BC004375 |
| Gene ID: | 1718 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cancer, Metabolism, Neuroscience, Cardiovascular |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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