Order NO. D623191
人SNAP23抗原(重组蛋白)
英文名 | Human SNAP23 Antigen (Recombinant Protein) | ||
别名 | SNAP-23; SNAP23A; SNAP23B; HsT17016 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D623191-0001 | 1 MG | 预计30日内发货 |
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D623191-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Recombinant protein corresponding to a region derived from 1-211 amino acids of human SNAP23
属性
Full name: | synaptosome associated protein 23 |
Synonyms: | SNAP-23; SNAP23A; SNAP23B; HsT17016 |
Swissprot: | O00161 |
Gene Accession: | BC003686 |
Gene ID: | 8773 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Neuroscience |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |