Order NO. D623556
VPS37A抗原(重组蛋白)
英文名 | VPS37A Antigen (Recombinant Protein) | ||
别名 | HCRP1; PQBP2; SPG53 | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D623556-0001 | 1 MG | 预计30日内发货 |
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D623556-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 224-397 amino acids of human VPS37A
属性
Full name: | VPS37A subunit of ESCRT-I |
Synonyms: | HCRP1; PQBP2; SPG53 |
Swissprot: | Q8NEZ2 |
Gene Accession: | BC022363 |
Gene ID: | 137492 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Signal Transduction |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012] (The background information is obtained from official databases and does not represent the product information.) |