Order NO. D623573
人WRAP53抗原（重组蛋白）
| 英文名 | Human WRAP53 Antigen (Recombinant Protein) | ||
| 别名 | DKCB3; TCAB1; WDR79 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D623573-0001 | 1 MG | 预计30日内发货 |
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| D623573-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 349-548 amino acids of human WRAP53
属性
| Full name: | WD repeat containing antisense to TP53 |
| Synonyms: | DKCB3; TCAB1; WDR79 |
| Swissprot: | Q9BUR4 |
| Gene Accession: | BC002336 |
| Gene ID: | 55135 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cell Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011] (The background information is obtained from official databases and does not represent the product information.) |
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