人UNC45B抗原（重组蛋白）,Human UNC45B Antigen (Recombinant Protein) 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

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Order NO. D624167

人UNC45B抗原（重组蛋白）

英文名	Human UNC45B Antigen (Recombinant Protein)
别名	CMYA4; UNC45; CTRCT43; SMUNC45; UNC-45B
相关类别	抗原	储存	冷冻（-20℃）
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D624167-0001	1 MG	预计30日内发货	待询价	待询价
D624167-0050	50 UG	预计30日内发货	待询价	待询价
D624167-0100	100 UG	预计30日内发货	待询价	待询价

产品描述

概述

Fusion protein corresponding to a region derived from 732-931 amino acids of human UNC45B

属性

Full name:	unc-45 myosin chaperone B
Synonyms:	CMYA4; MFM11; UNC45; CTRCT43; SMUNC45; UNC-45B
Swissprot:	Q8IWX7-3
Gene Accession:	BC101063
Gene ID:	146862
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Research areas:	Signal Transduction, Developmental Biology
Reconstitution:	Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background:	This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] (The background information is obtained from official databases and does not represent the product information.)

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