Order NO. D624167
人UNC45B抗原（重组蛋白）
| 英文名 | Human UNC45B Antigen (Recombinant Protein) | ||
| 别名 | CMYA4; UNC45; CTRCT43; SMUNC45; UNC-45B | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D624167-0001 | 1 MG | 预计30日内发货 |
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| D624167-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 732-931 amino acids of human UNC45B
属性
| Full name: | unc-45 myosin chaperone B |
| Synonyms: | CMYA4; MFM11; UNC45; CTRCT43; SMUNC45; UNC-45B |
| Swissprot: | Q8IWX7-3 |
| Gene Accession: | BC101063 |
| Gene ID: | 146862 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Signal Transduction, Developmental Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] (The background information is obtained from official databases and does not represent the product information.) |
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