Order NO. D624335
C1orf112抗原(重组蛋白)
英文名 | C1orf112 Antigen (Recombinant Protein) | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D624335-0001 | 1 MG | 预计30日内发货 |
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D624335-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 654-853 amino acids of human FIRRM
属性
Full name: | FIGNL1 interacting regulator of recombination and mitosis |
Synonyms: | FLIP; Apolo1; MEICA1; C1orf112 |
Swissprot: | Q9NSG2 |
Gene Accession: | BC107168 |
Gene ID: | 55732 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Research areas: | Cell Biology |
Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
Background: | Regulates PLK1 kinase activity at kinetochores and promotes faithful chromosome segregation in prometaphase by bridging kinase and phosphatase activities (PubMed:34260926). Phosphorylation of FIRRM by PLK1 negatively regulates its interaction with the phosphatase, PPP1CC, thus creating a negative feedback loop for maintaining proper PLK1 kinase activity during mitosis (PubMed:34260926). In complex with FIGL1 may regulate homologous recombination (PubMed:29608566). (The background information is obtained from official databases and does not represent the product information.) |