Order NO. D624486
CDC45抗原（重组蛋白）
| 英文名 | CDC45 Antigen (Recombinant Protein) | ||
| 别名 | CDC45L; CDC45L2; PORC-PI-1 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D624486-0001 | 1 MG | 预计30日内发货 |
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| D624486-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 367-566 amino acids of human CDC45
属性
| Full name: | cell division cycle 45 |
| Synonyms: | CDC45L; MGORS7; CDC45L2; PORC-PI-1 |
| Swissprot: | O75419 |
| Gene Accession: | BC006232 |
| Gene ID: | 8318 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Epigenetics and Nuclear Signaling, Cancer |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (The background information is obtained from official databases and does not represent the product information.) |
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