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Order NO. D624486
人CDC45抗原(重组蛋白)
英文名 Human CDC45 Antigen (Recombinant Protein)
别名 CDC45L; CDC45L2; PORC-PI-1
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D624486-0001 1 MG 预计30日内发货
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D624486-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 367-566 amino acids of human CDC45

属性

Full name: cell division cycle 45
Synonyms: CDC45L; MGORS7; CDC45L2; PORC-PI-1
Swissprot: O75419
Gene Accession: BC006232
Gene ID: 8318
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Epigenetics and Nuclear Signaling, Cancer
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (The background information is obtained from official databases and does not represent the product information.)
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