Order NO. D625243
人RNF111抗原（重组蛋白）
| 英文名 | Human RNF111 Antigen (Recombinant Protein) | ||
| 别名 | ARK; hRNF111 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D625243-0001 | 1 MG | 预计30日内发货 |
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| D625243-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 850-986 amino acids of human RNF111
属性
| Full name: | ring finger protein 111 |
| Synonyms: | ARK; hRNF111 |
| Swissprot: | Q6ZNA4 |
| Gene Accession: | BC010369 |
| Gene ID: | 54778 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Cell Biology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012] (The background information is obtained from official databases and does not represent the product information.) |
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