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Order NO. D625243
人RNF111抗原（重组蛋白）
英文名 Human RNF111 Antigen (Recombinant Protein)
别名 ARK; hRNF111
相关类别 抗原 储存 冷冻（-20℃）
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
D625243-0001 1 MG 预计30日内发货 待询价 待询价
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D625243-0050 50 UG 预计30日内发货 待询价 待询价
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D625243-0100 100 UG 预计30日内发货 待询价 待询价
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产品描述

概述

Fusion protein corresponding to a region derived from 850-986 amino acids of human RNF111

属性

Full name: ring finger protein 111
Synonyms: ARK; hRNF111
Swissprot: Q6ZNA4
Gene Accession: BC010369
Gene ID: 54778
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Cell Biology
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012] (The background information is obtained from official databases and does not represent the product information.)
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