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Order NO. D625578
人RPS19抗原(重组蛋白)
英文名 Human RPS19 Antigen (Recombinant Protein)
别名 ribosomal protein S19; DBA; S19; DBA1; eS19; LOH19CR1
相关类别 抗原 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D625578-0001 1 MG 预计30日内发货
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D625578-0100 100 UG 预计30日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 2-145 amino acids of human RPS19

属性

Full name: ribosomal protein S19
Synonyms: DBA; S19; DBA1; eS19; LOH19CR1
Swissprot: P39019
Gene Accession: BC000023
Gene ID: 6223
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Epigenetics and Nuclear Signaling
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
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