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Order NO. D625915
人ZAP70抗原（重组蛋白）
英文名 Human ZAP70 Antigen (Recombinant Protein)
别名 SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
相关类别 抗原 储存 冷冻（-20℃）
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
D625915-0001 1 MG 预计7日内发货
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D625915-0050 50 UG 预计7日内发货
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D625915-0100 100 UG 预计7日内发货
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产品描述

概述

Fusion protein corresponding to a region derived from 420-619 amino acids of human ZAP70

属性

Full name: zeta chain of T cell receptor associated protein kinase 70
Synonyms: SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70
Swissprot: P43403
Gene Accession: BC039039
Gene ID: 7535
Purity: >85%, as determined by Coomassie blue stained SDS-PAGE
Expression system: Escherichia coli
Tags: His tag C-Terminus, GST tag N-Terminus
Research areas: Signal Transduction, Immunology
Reconstitution: Reconstitute with sterile distilled water or deionized water to 1 mg/ml
Background: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.)
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Sample Application

  • Purified Human ZAP70 Recombinant Protein (Catalog number: D625915) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.
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