Order NO. D625915
ZAP70抗原（重组蛋白）
| 英文名 | ZAP70 Antigen (Recombinant Protein) | ||
| 别名 | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D625915-0001 | 1 MG | 预计30日内发货 |
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| D625915-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 420-619 amino acids of human ZAP70
属性
| Full name: | zeta chain of T cell receptor associated protein kinase 70 |
| Synonyms: | SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70 |
| Swissprot: | P43403 |
| Gene Accession: | BC039039 |
| Gene ID: | 7535 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Signal Transduction, Immunology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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