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Order NO. D660788
VEGFA 抗原（多肽片段）
英文名 VEGFA Antigen (Peptide fragment)
相关类别 抗原 储存 冷冻（-20℃）
编 号 包装 库存 目录价（￥） 您的价格（￥） 数 量
D660788-0001 1 MG 预计30日内发货
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产品描述

概述

Synthetic peptide corresponding to a region derived from 130-143 amino acids of human vascular endothelial growth factor A

属性

Full name vascular endothelial growth factor A
Synonyms VPF, VEGF, MVCD1
Swissprot P15692
Gene Accession NP_001020537
Background This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
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