Order NO. T510018
人Pro-Adrenomedullin (N-20)肽
| 英文名 | Pro-Adrenomedullin (N-20), human | ||
| 相关类别 | 多肽 | 储存 | 冷冻（-20℃） |
| 分子量 | 2460.9 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| T510018-0001 | 1.0 MG | 现货 |
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产品描述
概述
肾上腺髓质素前体含肾上腺髓质素前体NH2末端20肽（PAMP），一个独特的20残基序列。给药后，PAMP对麻醉大鼠产生强烈而迅速的降压作用。PAMP也被认为是肾去甲肾上腺素能神经递质的抑制性调节剂，在肾功能的调节中起重要作用。PAMP被认为是体内肾上腺儿茶酚胺释放的抑制调节因子，在禁食小鼠第三脑室注射后具有显著的高血糖效应。
属性
| 序列(三个字母） | Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2 |
| 序列（一个字母） | ARLDVASEFRKKWNKWALSR-NH2 |
| CAS | [150238-87-2] |
| 纯度 | ≥95.0% |
| 分子量 | 2461.8 |
| Description | Precursor of adrenomedullin containing proadrenomedullin NH2-terminal 20 peptide (PAMP), a unique 20-residue sequence. When administered, PAMP produces a strong and rapid hypotensive effect in anesthetized rats. PAMP has also been suggested to function as an inhibitory modulator of renal noradrenergic neurotransmission, thereby playing an important role in the regulation of renal functions. PAMP has been proposed to serve as an inhibitory regulator in adrenal catecholamine release in vivo and possesses a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice. |
| Formula | C112H178N36O27 |