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Order NO. T510071
Insulin B (9 - 23)肽
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
T510071-0001 | 1.0 MG | 咨询 | 待询价 | 待询价 |
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属性
序列(三个字母) | Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly |
序列(一个字母) | SHLVEALYLVCGERG |
纯度 | ≥95.0% |
分子量 | 1645.9 |
Description | This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis. |
Formula | C72H116N20O22S |
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