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Order NO. T510071
Insulin B (9 - 23)肽
英文名 Insulin B (9 - 23)
相关类别 多肽 储存 冷冻(-20℃)
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
T510071-0001 1.0 MG 现货
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属性

序列(三个字母) Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly
序列(一个字母) SHLVEALYLVCGERG
纯度 ≥95.0%
分子量 1645.9
Description This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
Formula C72H116N20O22S
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